
R-421A Refrigerant 25 lb
Direct R-22 retrofit for A/C systems. Sealed factory-direct cylinder, shipped free anywhere in the continental US.
- Free US shipping — no order minimum
- 90-day money-back guarantee
- Sealed, DOT-certified disposable cylinder
- AHRI 700 purity specification
90-Day Money-Back Guarantee. Ordered the wrong grade, or the job changed? Send any unopened cylinder back within 90 days for a full refund — no restocking fee, return shipping on us.
90-day money-back guarantee
Send any unopened cylinder back within 90 days for a full refund. No restocking fee, return shipping covered.
Free shipping, no minimum
Every cylinder ships free in the continental US — one unit or a full pallet, same price.
Talk to a real tech
Questions on grade selection or retrofit compatibility? Our team answers before you buy, not after.
About R-421A
A two-component R-22 retrofit built around service simplicity: it is compatible with the mineral oil already in the system, so no flush or oil change is required. That makes it a fast, low-labour option for ageing R-22 air conditioning where a full POE conversion isn't economic to justify.
- No oil change — works with existing mineral oil
- Two components only, simpler than 5-part blends
- Suits R-22 A/C and heat pump service
- Non-flammable A1 classification
- GWP (AR4)
- 2,631
- Safety class
- A1
- Lubricant
- Mineral oil, AB or POE
- Class
- HFC
Where R-421A is used
Direct R-22 retrofit for A/C systems. Always confirm the grade against the equipment nameplate before charging.
- Existing R-22 residential split systems
- Legacy commercial A/C and heat pumps
- Direct-expansion retrofit conversions
- Service work on pre-2010 equipment
What ships
1 × 25 lb R-421A cylinder
Factory-sealed disposable cylinder with intact tamper seal and valve cap.
Batch and lot tagging
Every cylinder carries its fill batch and lot number for traceability on your job records.
Certificate of analysis
Purity documentation to the AHRI 700 specification, available on request for any lot.
Safety data sheet
Current SDS ships with the order and is available for download before you buy.
Specifications
- Refrigerant
- R-421A
- Net weight
- 25 lb
- Composition
- R-125 / R-134a (58/42)
- Chemical class
- HFC
- ASHRAE safety group
- A1
- GWP (AR4, 100-yr)
- 2,631
- Compatible lubricant
- Mineral oil, AB or POE
- Replaces
- R-22
- Typical application
- Direct R-22 retrofit for A/C systems
- System category
- Legacy / Retrofit
- Cylinder
- Disposable, DOT-certified
- Purity
- AHRI 700 compliant
Ordering & returns
Free ground shipping
Orders placed before 2pm ET ship the same business day, free anywhere in the continental US.
Certificate of analysis
AHRI 700 purity documentation available on request for any lot.
90-day money-back guarantee
Unopened cylinders in original condition can be returned within 90 days for a full refund, return shipping covered. Damaged or incorrect shipments are replaced at our cost.
Compare legacy / retrofit grades
Other grades we stock for the same class of equipment.
How ordering works
Pick your quantity
Volume pricing applies automatically — up to 20% off per cylinder at 10 units. No codes, no minimum order.
Check out in minutes
Enter payment and shipping details — takes under a minute. Save your info for even faster reorders.
Ships same day
Orders placed before 2pm ET go out the same business day, free anywhere in the continental US.
Questions about this product
Pricing is per cylinder and drops as you add more — 5% off at 2, 10% at 4, 15% at 6, and 20% at 10. The discount applies automatically when you pick a tier; there's no code to enter.
Buying past 10 cylinders?
Shops running pallet volume get quoted directly. Send the grades and quantities you go through in a typical month and we'll price it — plus keep your certification on file so reorders ship same day.



